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Observational Study
Contributing Factors to Early Recurrence of Ventricular Fibrillation during Out-of-hospital Cardiac Arrest: an Observational Retrospective Study.
- Daniel Jost, Hong Tuan HaVivienVParis Fire Brigade, Emergency Medical Department, France., Julie Trichereau, Benoit Frattini, Clément Derkenne, Sabine Lemoine, Frédéric Lemoine, Romain Jouffroy, Romain Ked... more
- Paris Fire Brigade, Emergency Medical Department, France; Sudden Death Expertise Center, INSERM U.970, Paris, France. Electronic address: daniel.jost@pompiersparis.fr.
- Resuscitation. 2020 Sep 1; 154: 19-24.
IntroductionIn out-of-hospital cardiac arrest (OHCA), external electric shock (EES) is recommended for treating ventricular fibrillation (VF). Refibrillation commonly occurs within one minute post-shock. We aimed to investigate refibrillation times and identifyclinical and electrical factors associated with them.Materials And MethodsThis retrospective observational study, based on the Paris Fire Brigade database, included non-traumatic OHCA over 18 years of age who received at least one shock with an AED from Basic Life Support (BLS) rescuers and from which we randomly selected a sample to measure the refibrillation-times. Without prior reference to it in the literature, we classified the refibrillation-time into two modalities according to whether it was above or below the median-time. We performed multiple regression analysis to assess associations between refibrillation-time and potential explanatory factors.ResultsAmong 13,181 patients who experienced OHCA from January 2010 to January 2014, we analysed AED data from 215 patients (590 shocks), 82.1% males, median age 61[IQR: 52-75] years. Most of them occurred at home (57%), were witnessed (87%), and were shockable (88.8%). A median of 5[4-7] EES/patients were delivered. The median-time from shock to refibrillation was 25[13-44] s. Multivariate analysis showed that a shorter post-shock hands-off time favoured earlier refibrillation (p = 0.034), as well as older age (p = 0.002) (Fig. 2, Supplementary table).ConclusionIn non-traumatic OHCA, most refibrillations occurred within 45-s post-shock. Age and post-shock hands-off time were the two contributing factors to time to refibrillation.Copyright © 2020 Elsevier B.V. All rights reserved.
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