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- J C Gerster, R Bossy, and J Dudler.
- University Rheumatology and Rehabilitation Center, CHUV, Lausanne, Switzerland.
- J Rheumatol. 1999 Dec 1; 26 (12): 2695-7.
AbstractWe describe 2 men with seronegative rheumatoid arthritis who presented non-union of bone after osteotomy of the tibia in one case and of a metatarsal bone in the second. Both patients were still being treated with oral low doses of methotrexate (MTX). After MTX was stopped, a prompt healing of the bone occurred. These observations suggest that MTX should be stopped temporarily in cases with delayed bone healing after surgery.
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