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Case Reports
Exceptional response of brain metastases to short course nivolumab while on high-dose steroids.
- W K de Jong, A C M Mulders, W Westendorp, and A Becker.
- Department of Pulmonology, Hospital Gelderse Vallei, Ede, the Netherlands.
- Neth J Med. 2019 Dec 1; 77 (9): 338-340.
AbstractIn this manuscript, we describe a patient with an exceptional response of brain metastases from lung cancer to short course nivolumab while on high-dose steroids. This case shows that immunotherapy can cause delayed and enduring responses even in patients with poor predictive parameters for treatment success, such as low programmed death ligand-1 (PDL1) expression and long-term treatment with high-dose corticosteroids. Secondly, it underscores the importance of follow up after the administration of immunotherapy, even in cases with a deemed poor prognosis and few received cycles of immunotherapy.
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