• Neth J Med · Dec 2019

    Case Reports

    Epstein-Barr virus infection or malignant lymphoma - what you see is not what you get.

    • I de Haes, J Versluis, K H Lam, Jongen J L M JLM, J K Doorduijn, and S Kuipers.
    • Department of Haematology, Erasmus Medical Centre Cancer Institute, Rotterdam, the Netherlands.
    • Neth J Med. 2019 Dec 1; 77 (10): 370-372.

    AbstractInfectious mononucleosis may mimic lymphoma, both clinically and histopathologically. We present a patient with neurological symptoms and lymphadenopathy, initially diagnosed as Epstein-Barr virus (EBV)-positive angioimmunoblastic T-cell lymphoma (AITL) with cerebrospinal fluid (CSF) localisation based on lymph node pathology and a 30-fold higher EBV load in the CSF compared with serum. However, the patient fully recovered spontaneously and EBV became negative in both CSF and serum, suggestive of a dramatic presentation of EBV meningoencephalitis.

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