• Neuromodulation · Apr 2008

    Effect of subthalamic nucleus stimulation on severe striatal hand deformity in Parkinson's disease: a case report.

    • Takashi Morishita, Yoichi Katayama, Kazutaka Kobayashi, Hideki Oshima, Chikashi Fukaya, and Takamitsu Yamamoto.
    • Division of Neurosurgery, Department of Neurological Surgery, and Division of Applied System Neuroscience, Department of Advanced Medical Science, Nihon University School of Medicine, Tokyo, Japan.
    • Neuromodulation. 2008 Apr 1;11(2):124-7.

    AbstractStriatal hand is a deformity encountered in Parkinson's disease and other parkinsonisms. It is characterized by extension that occurs at all the interphalangeal joints, flexion at the metacarpophalangeal joints, and ulnar deviation. It can be differentiated from levodopa-induced dystonia and primary dystonia, since the deformity exists continuously even during sleep. We experienced a case of Parkinson's disease with severe striatal hand deformity which was successfully treated by deep brain stimulation of the subthalamic nucleus (STN-DBS). Although the precise mechanism remains unclear, rigidity is assumed to contribute to the limb deformities. Based on our experience, it seems possible therefore that the effect of STN-DBS on the hand deformity was a secondary effect on muscular rigidity. STN-DBS is assumed to represent a useful treatment option for striatal hand deformity.© 2008 International Neuromodulation Society.

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