• Isabel Pérez-Martínez, Luis Rodrigo, and Alfredo J Lucendo.
• Servicio de Aparato Digestivo, Hospital Universitario Central de Asturias, Oviedo, España.
• Med Clin (Barc). 2019 Jun 7; 152 (11): 444-449.

AbstractEosinophilic oesophagitis is a unique form of non-IgE-mediated food allergy characterised by oesophageal eosinophilic infiltration. The prevalence of EoE has grown to currently represent the first cause of dysphagia and food impaction in children and young adults. Avoiding food triggers is the only therapy targeting the cause of the disease, but none of the currently available food allergy tests adequately predicts food triggers for EoE. Strategies based on the empirical elimination of food are the most effective and convenient in clinical practice. Proton pump inhibitors constitute an effective first-line therapy in half of patients, through a direct anti-inflammatory effect independent of its action on gastric acid secretion. Topical glucocorticosteroids budesonide and fluticasone reduce eosinophilic inflammation and reverse symptoms. This review includes the most relevant aspects of the epidemiology, diagnosis, treatment and monitoring of eosinophilic oesophagitis.Copyright © 2018 Elsevier España, S.L.U. All rights reserved.

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