• Turk J Med Sci · Feb 2019

    Observational Study

    Evaluation of myocardial dispersion of repolarization in patients with heart transplantation

    • Cengiz Burak, Erkan Baysal, Muhammed Süleymanoğlu, Çağrı Yayla, Serkan Cay, and Ümit Kervan.
    • Turk J Med Sci. 2019 Feb 11; 49 (1): 212-216.

    Background/AimThe number of patients with heart transplantation has dramatically increased in the last decade. Considerable studies have suggested that the interval from the peak to the end of the electrocardiographic T wave (Tp-e) may correspond to the transmural dispersion of repolarization and increased Tp-e interval and Tp-e/QT ratio are associated with malignant ventricular arrhythmias. We analyzed the dispersion of myocardial repolarization using electrocardiographic Tp-e interval and Tp-e/QTc ratio in patients with heart transplantation.Materials And MethodsThis observational study included 38 patients (12 female and 26 male) with heart transplantation and 38 well-matched controls. From electrocardiograms, Tp-e interval and Tp-e/QTc ratio were calculated and compared between the 2 groups.ResultsNoninvasive arrhythmia indicators including Tp-e interval (84.63 ± 14.17 ms vs 71.82 ± 7.47 ms, P < 0.001), Tp-e/QTc ratio (0.19 ± 0.04 vs 0.16 ± 0.02, P < 0.001) and QTc interval except QT interval were significantly higher in transplanted hearts compared to normal hearts.ConclusionPatients with heart transplantation have increased myocardial dispersion of repolarization.

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