• Aust Prescr · Jun 2020

    Review

    Lithium therapy and its interactions.

    • Gin S Malhi, Erica Bell, Tim Outhred, and Michael Berk.
    • Discipline of Psychiatry, Northern Clinical School, University of Sydney.
    • Aust Prescr. 2020 Jun 1; 43 (3): 91-93.

    AbstractLithium is one of the most effective mood stabilisers for people with a mood disorder. However, many of these patients are also taking other medicines that could potentially interact with lithium To minimise the risk of relapse, it is usually necessary to maintain the lithium serum concentration between 0.6 mmol/L and 0.8 mmol/L Lithium clearance is easily influenced by drugs that alter renal function such as ACE inhibitors, angiotensin receptor antagonists, diuretics, and non-steroidal anti-inflammatory drugs It is therefore prudent for prescribers to monitor and adjust the lithium dose to avoid adverse effects or loss of efficacy(c) NPS MedicineWise 2020.

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