• Int J Clin Exp Med · Jan 2014

    Case Reports

    Surgical treatment and radiotherapy of epidermoid cyst with malignant transformation in cerebellopontine angle.

    • Rui Feng, Xin Gu, Jie Hu, Liqin Lang, Haixia Bi, Jun Guo, and Li Pan.
    • Department of Neurosurgery, Huashan Hospital, Fudan University Shanghai 200040, China.
    • Int J Clin Exp Med. 2014 Jan 1; 7 (1): 312-5.

    AbstractWe report surgical treatment and radiotherapy of an extremely rare case of malignant epidermoid cyst located in cerebellopontine angle. MRI and CT demonstrated the lesion with partial enhancement and calcification. During operation, we found the tumor attached tightly to surrounding tissue. Finally we achieved near total resection of it. Histopathology confirmed the diagnosis of epidermoid cyst with malignant transformation. With adjuvant radiotherapy, the patient underwent excellent recovery, and follow-up MRI demonstrated no obvious residue or recurrence of the tumor. Malignant epidermoid cyst can be diagnosed radiologically in combination with clinical presentation. Maximal removal plus adjuvant radiotherapy is the treatment of choice, although the general prognosis of it is poor.

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