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- Danièle Debruyne, Marie-Anne Courné, Reynald Le Boisselier, Samira Djezzar, Marie Gérardin, Alexandra Boucher, Laurent Karila, Antoine Coquerel, and Michel Mallaret.
- CEIP Addictovigilance, CHU, Caen, France. debruyne-d@chu-caen.fr
- Therapie. 2010 Nov 1; 65 (6): 519-24.
AbstractDesigner drugs are currently marketed as substitutes for stimulant drugs as cocaine, amphetamine, MDMA...Unlike compounds listed as narcotics, these new substances are deliberately synthesized to avoid anti-drug laws. Among them, mephedrone (4-methylmethcatinone) that belongs to cathinone family, has been recently introduced in France. Users report positive euphoric and entactogenic effects. They also describe negative effects such as increased dependence towards the drug itself and larger craving for tobacco and alcohol. The numerous and various described adverse effects include psychoactive, digestive, cardiovascular... effects. Some fatality cases have been reported in scientific literature or in press and attributed to mephedrone often in association with other substances. Mephedrone has been listed as narcotic in several European countries and more recently in France.© 2010 Société Française de Pharmacologie et de Thérapeutique.
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