• Y Wang and K Wan.
• Department of Stomatology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
• Zhonghua Kou Qiang Yi Xue Za Zhi. 2019 Apr 9; 54 (4): 282-285.

AbstractNitrous oxide (N(2)O), also known as laughing gas, is widely used in the dental offices as a common inhaled sedative analgesic gas to reduce anxiety and pain during treatment. Studies have shown that long-term exposure to higher concentrations of laughing gas may have a certain impact on the health of medical staff, while currently research on iatrogenic pollution in applications of laughing gas in oral therapy is not sufficient. In the United States and Europe, the condition of applications of laughing gas is relativrly mature, and there are related regulations and recommended measures to prevent and control iatrogenic pollution. However, studies in these countries still show that there is iatrogenic pollution in the clinical use of laughing gas and lack of uniform detection measures. While, in China, there is little research on the health effects of laughing gas on medical staff and on how to detect and control nitrous oxide pollution. This review is about the hazards, monitoring and control of clinical application of nitrous oxide.

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