• Internal medicine · Jan 2020

    Case Reports

    Tuberculous Spondylitis Caused by Intravesical Bacillus Calmette-Guerin Therapy.

    • Tomokazu Minakata, Yoshio Nakano, Shinobu Tamura, Yamanishi Kazuki, Kana Hayakawa, Takahiro Hayakawa, Takayuki Oota, Tokuzou Fuzimoto, Yukiko Yamano, and Takemasa Takii.
    • Department of Nephrology, Kinan Hospital, Japan.
    • Intern. Med. 2020 Jan 1; 59 (5): 733-737.

    AbstractA 74-year-old man underwent intravesical bacillus Calmette-Guerin (BCG) therapy for bladder cancer and later presented with lower left back pain. Magnetic resonance imaging of the spine showed high signal intensity, diagnosed as a cystic lesion in the epidural and bilateral intestinal psoas muscle. A computed tomography-guided needle biopsy and histological examination revealed bacteria from the family Mycobacteriaceae, and Mycobacterium bovis was identified using multiplex polymerase chain reaction. If lower back pain appears in a patient who has undergone BCG therapy, it is necessary to test for tuberculous spondylitis. In addition, QuantiFERON is useful for the differential diagnosis of M. bovis BCG infection.

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