• Zixing Tian, Michael Stedman, Martin Whyte, Simon G Anderson, George Thomson, and Adrian Heald.
• Faculty of Biology, Medicine and Health, Medicine and Health, Manchester Academic Health Science Centre, the University of Manchester, Manchester, UK.
• Int. J. Clin. Pract. 2020 Nov 1; 74 (11): e13617.

BackgroundThe worldwide outbreak of coronavirus disease-19 (COVID-19) has already put healthcare workers (HCWs) at a high risk of infection. The question of how to give HCWs the best protection against infection is a priority.MethodsWe searched systematic reviews and original studies in Medline (via Ovid) and Chinese Wan Fang digital database from inception to May, 2020, using terms 'coronavirus', 'health personnel', and 'personal protective equipment' to find evidence about the use of full-body PPEs and other PPEs by HCW exposed highly infectious diseases.ResultsCovering more of the body could provide better protection for HCWs. Of importance, it is not just the provision of PPE but the skills in donning and doffing of PPE that are important, this being a key time for potential transmission of pathogen to the HCW and in due time from them to others. In relation to face masks, the evidence indicates that a higher-level specification of face masks and respirators (such as N95) seems to be essential to protect HCWs from coronavirus infection. In community setting, the use of masks in the case of well individuals could be beneficial. Evidence specifically around PPE and protection from the COVID-19 virus is limited.ConclusionCovering more of the body, and a higher-level specification of masks and respirators could provide better protection for HCWs. Community mask usecould be beneficial. High quality studies still need to examine the protection of PPE against COVID-19.© 2020 John Wiley & Sons Ltd.

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