• Atencion primaria · Aug 2019

    [Management of hyperglycaemia with non-insulin drugs in adult patients with type 2 diabetes].

    • Fernando Álvarez-Guisasola, Domingo Orozco-Beltrán, Ana M Cebrián-Cuenca, Manuel Antonio Ruiz Quintero, Escarlata Angullo Martínez, Luis Ávila Lachica, Carlos Ortega Millán, Elena Caride Miana, Jorge Navarro-Pérez, Julio Sagredo Perez, Joan Barrot de la Puente, and Francesc Xavier Cos Claramunt.
    • Medicina Familiar y Comunitaria, Centro de Salud Ribera del Órbigo, Benavides de Órbigo, León, España.
    • Aten Primaria. 2019 Aug 1; 51 (7): 442451442-451.

    AbstractTreatment of diabetes mellitus type2 (DM2) includes healthy eating and exercise (150minutes/week) as basic pillars. For pharmacological treatment, metformin is the initial drug except contraindication or intolerance; in case of poor control, 8 therapeutic families are available (6 oral and 2 injectable) as possible combinations. An algorithm and some recommendations for the treatment of DM2 are presented. In secondary cardiovascular prevention, it is recommended to associate an inhibitor of the sodium-glucose cotransporter type 2 (iSGLT2) or a glucagon-like peptide-1 receptor agonist (arGLP1) in patients with obesity. In primary prevention if the patient is obese or overweight metformin should be combined with iSGLT2, arGLP1, or inhibitors of type4 dipeptidylpeptidase (iDPP4). If the patient does not present obesity, iDPP4, iSGLT2 or gliclazide, sulfonylurea, recommended due to its lower tendency to hypoglycaemia, may be used.Copyright © 2019. Publicado por Elsevier España, S.L.U.

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