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- J de Sèze and C Arndt.
- Service de neurologie, CHU de Strasbourg, 1, place de l'hôpital, 67091 Strasbourg cedex, France. jerome.de.seze@chru-strasbourg.fr
- Rev Neurol France. 2010 Dec 1; 166 (12): 966-9.
AbstractInflammatory optic neuritis (ON) represents a frequent clinical situation in neurology and ophthalmology. When MRI and CSF analysis are normal, ON is considered idiopathic with a suspected viral etiology. However, in several cases either a recurrence or a myelitis may occur. In the first case, it is relapsing inflammatory optic neuritis (RION) and in the second case it is neuromyelitis optica (NMO). Nevertheless, predictive criteria of a recurrence or an extension of the disease to spinal cord remains unknown, excepted for anti-NMO IgG antibodies which are probably highly specific for a future evolution to NMO. In the present paper, the authors successively present the two clinical situations (RION and NMO) and attempt to summarize diagnostic and prognostic criteria.Copyright © 2010 Elsevier Masson SAS. All rights reserved.
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