• H Mesrar, J Mesrar, B Maillier, S Kraoua, L Chapoutot, and B Delclaux.
• Service de cardiologie, centre hospitalier de Troyes, 101, avenue Anatole-France, 10000 Troyes, France; Service de pneumologie, centre hospitalier de Troyes, 101, avenue Anatole France, 10000 Troyes, France. Electronic address: Hicham.mesrar37@gmail.com.
• Rev Med Interne. 2018 May 1; 39 (5): 339-345.

AbstractLemierre's syndrome is a rare and severe sepsis that can rapidly lead to a life-threatening condition in the absence of early management. This syndrome described at the beginning of the 20th century combines oropharyngeal infection complicated with septic thrombosis of the internal jugular vein and septic emboli predominantly pulmonary. Fusobacterium necrophorum, anaerobic germ, Gram negative bacillus is the main germ in this "necrobacillosis". The diagnosis is should be confirmed precociously with cervicothoracic CT-scan, reference exam, and bacteriological examinations (especially in atypical forms). Its management consists of an emergency antibiotic treatment, combining a third-generation cephalosporin or a betalactam with metronidazole, anticoagulant therapy to be reserved for high-risk situations related to thrombosis. Surgical treatment may be required.Copyright © 2017 Société Nationale Française de Médecine Interne (SNFMI). Published by Elsevier SAS. All rights reserved.

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