• Patricia A Lincoln, Katherine Whelan, Lauren P Hartwell, Kimberlee Gauvreau, Brenda L Dodsen, Joan M LaRovere, Ravi R Thiagarajan, Patricia A Hickey, and Curley Martha A Q MAQ Department of Cardiovascular and Critical Care Nursing Services, Boston Children's Hospital, Boston, MA. .
• Department of Cardiovascular and Critical Care Nursing Services, Boston Children's Hospital, Boston, MA.
• Pediatr Crit Care Me. 2020 Dec 1; 21 (12): 1064-1070.

ObjectivesTo assess the impact of a nurse-implemented goal-directed sedation strategy on patient care and nursing practice in a pediatric cardiac ICU.DesignQuality improvement project with a pre-post interval measurement plan.SettingThirty-one bed pediatric cardiac ICU in a freestanding tertiary care children's hospital.PatientsPostoperative pediatric cardiac surgery patients.InterventionsThe implementation of cardiac-Randomized Evaluation of Sedation Titration for Respiratory Failure (RESTORE), a nurse-implemented goal directed strategy to improve pain and sedation management in a pediatric cardiac ICU which included daily team discussion of the patient's trajectory of illness (acute, titration, or weaning phase), prescription of a sedation target score based on the patient's trajectory of illness, arousal assessments, and opioid and/or sedative titration. Withdrawal Assessment Scores were used to assess and manage iatrogenic withdrawal symptoms.Measurements And Main ResultsData related to opioid and sedation use, pain and sedation scores, and the occurrence and management of iatrogenic withdrawal symptoms were reviewed on 1,243 patients during four separate time periods: one pre-implementation and three discontinuous post-implementation time intervals. Patient age and complexity were consistent across the data collection periods. Post-implementation opioids and benzodiazepines use was reduced about 50% without a concomitant increase in the use of other sedative classes. Few post-intervention patients were discharged from the pediatric cardiac ICU or to home on methadone (pediatric cardiac ICU: pre 19% to post 3%; hospital: pre 12% to post 1.3%). Documentation of pain, sedation, and withdrawal scores became more consistent and nurses reported satisfaction with their patient's comfort management.ConclusionsThe implementation of a nurse-driven goal-directed plan such as cardiac-RESTORE to manage pediatric cardiac ICU patient pain and sedation is possible, sustainable, and associated with reduced sedative and methadone use.

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