• Internal medicine · Dec 2020

    Case Reports

    An Autopsy Case of Lambl's Excrescences with Trousseau Syndrome that Caused Cardioembolic Stroke.

    • Takehisa Hirayama, Harumi Morioka, Hideomi Fujiwara, Konosuke Iwamoto, Tetsuhito Kiyozuka, Hiroteru Takeo, Ken Ikeda, and Osamu Kano.
    • Department of Neurology, Toho University Omori Medical Center, Japan.
    • Intern. Med. 2020 Dec 1; 59 (23): 3085-3088.

    AbstractThe frequency and risk of embolism by Lambl's excrescences (LEs) remain unclear. We herein report an autopsy case of LEs that caused cardioembolic stroke. A 74-year-old man with colon cancer was hospitalized for ischemic stroke. His D-dimer levels were elevated. Thus, a diagnosis of ischemic stroke with Trousseau syndrome was made. At the autopsy, we found LEs in the aortic valves and thromboembolism of the brain blood vessels. This finding demonstrated that fibrin clots had adhered to the LEs because of coagulation abnormalities associated with Trousseau syndrome and became embolized. This case highlights the risk of LEs in patients with coagulation abnormalities.

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