• Kasra Khatibi, Ponce Mejia Lucido Luciano LL Department of Radiological Sciences, Division of Interventional Neuroradiology, University of California Los Angeles, Los Angeles, Californi, Naoki Kaneko, Yinn Ooi, Tania Kaprealian, Nestor R Gonzalez, Nader Pouratian, and Viktor Szeder.
• Department of Radiological Sciences, Division of Interventional Neuroradiology, University of California Los Angeles, Los Angeles, California, USA. Electronic address: Kkhatibi@mednet.ucla.edu.
• World Neurosurg. 2020 Nov 1; 143: 332-335.

BackgroundNeoplastic cerebral aneurysms are rare presentations of cardiac myxomas. The natural history of such aneurysms is not well understood, and the optimal treatment strategy remains unclear. Clipping and coiling are effective, although can carry significant morbidity. Chemotherapy and radiation can theoretically be effective, although their clinical efficacy remains to be proven.Case DescriptionHere we describe a patient with cardiac myxoma presenting with multiple progressively fusiform aneurysms. These aneurysms were noted to be growing during conservative monitoring given the eloquent location. Subsequently, the patient underwent multiple sessions of targeted radiation therapy, which lead to obliteration, shrinkage, or halting in growth of these aneurysms.ConclusionsLow-dose targeted radiation therapy can be safe and effective in treatment of neoplastic myxomatous aneurysms.Copyright © 2020 Elsevier Inc. All rights reserved.

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