• Yu Chen, Fang Feng, Min Li, Jiao-Jiao Yuan, Xue-Ni Chang, Bao-Hua Wei, Hang Du, and Chen-Ming Dong.
• Department of Intensive Care Unit, Lanzhou University Second Hospital, Lanzhou, Gansu, China.
• J Chin Med Assoc. 2020 Nov 1; 83 (11): 1004-1007.

BackgroundTo explore the potential role of the platelet/lymphocyte ratio (PLR) as a prognostic marker in septic patients with acute kidney injury (AKI) and to provide theoretical evidence for the epidemiological study of the prognosis of patients with septic AKI in its early stage.MethodsA pilot study was conducted. A logistic regression analysis was conducted to screen the risk factors, and the selected factors were performed using multiple logistic regression analysis; a Receiver Operating Characteristic curve was used to determine the optimal cutoff value of the PLR and then to calculate the sensitivity and specificity of the PLR ratio.ResultsMechanical ventilation, platelet count, PLR, and arterial blood lactate concentration have a correlation with sepsis (p < 0.05). An elevated PLR is significantly associated with a worse prognosis of sepsis-induced AKI (higher mortality).ConclusionThe PLR might be an effective factor in predicting a worse prognosis of septic AKI patients.

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