• Niger J Clin Pract · Aug 2020

    Diagnostic accuracy of random plasma glucose and random blood capillary glucose in detecting international association of diabetes and pregnancy study groups- defined hyperglycemia in early pregnancy.

    • A S Adefisan, B N Olagbuji, A A Adeniyi, I P Ade-Ojo, S M Ghazalli, and B A Olofinbiyi.
    • Department of Obstetrics and Gynaecology, Ekiti State University Teaching Hospital, Ado Ekiti, Ekiti State, Nigeria.
    • Niger J Clin Pract. 2020 Aug 1; 23 (8): 1087-1094.

    BackgroundMaternal hyperglycemia first diagnosed in pregnancy, previously referred to as gestational diabetes mellitus is associated with health consequences for both the mother and her fetus/baby, not only in the short term but also in the long term. Early screening helps to identify women with overt diabetes or those with early onset GDM.AimsThe aim of this study was to determine the diagnostic performance of two screening tests (Random plasma glucose, Random capillary glucose) in relation to 75g Oral glucose tolerance test (OGTT) done before 24 weeks gestation.MethodsThis prospective longitudinal cohort study was carried out between 1st February, 2017 and 31st July, 2017, at two teaching hospitals in Nigeria. Two hundred and eighty one (281) pregnant women who met the inclusion criteria were selected and screened with both random plasma glucose (RPG) and random capillary glucose (RCG) before 24 weeks of pregnancy. They were then made to undergo 75g OGTT a week later. The diagnostic performance of the screening tests were determined.ResultsA total of 270 women had 75g OG.ConclusionRandom plasma glucose and Random capillary glucose performed poorly compared to 75g-OGTT in detecting hyperglycemia in early pregnancy.

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