• Esmaeel R Dadashzadeh, Lauren V Huckaby, Robert Handzel, M Shanaz Hossain, Gloria D Sanin, Vincent P Anto, Patrick Bou-Samra, J B Moses, Stephen Cai, Heather M Phelos, Richard L Simmons, Matthew R Rosengart, and Dirk J van der Windt.
• Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA.
• Ann. Surg. 2022 Feb 1; 275 (2): e488e495e488-e495.

ObjectiveThe aim of the study was to quantify the risk of incarceration of incisional hernias.BackgroundOperative repair is the definitive treatment for incisional ventral hernias but is often deferred if the perceived risk of elective operation is elevated secondary to comorbid conditions. The risk of incarceration during nonoperative management (NOM) factors into shared decision making by patient and surgeon; however, the incidence of acute incarceration remains largely unknown.MethodsA retrospective analysis of adult patients with an International Classification of Diseases, Ninth Revision or Tenth Revision diagnosis of incisional hernia was conducted from 2010 to 2017 in 15 hospitals of a single healthcare system. The primary outcome was incarceration necessitating emergent operation. The secondary outcome was 30-, 90-, and 365-day mortality. Univariate and multivariate analyses were used to determine independent predictors of incarceration.ResultsAmong 30,998 patients with an incisional hernia (mean age 58.1 ± 15.9 years; 52.7% female), 23,022 (78.1%) underwent NOM of whom 540 (2.3%) experienced incarceration, yielding a 1- and 5-year cumulative incidence of 1.24% and 2.59%, respectively. Independent variables associated with incarceration included: age older than 40 years, female sex, current smoker, body mass index 30 or greater, and a hernia-related inpatient admission. All-cause mortality rates at 30, 90, and 365 days were significantly higher in the incarceration group at 7.2%, 10%, and 14% versus 1.1%, 2.3%, and 5.3% in patients undergoing successful NOM, respectively.ConclusionsIncarceration is an uncommon complication of NOM but is associated with a significant risk of death. Tailored decision making for elective repair and considering the aforementioned risk factors for incarceration provides an initial step toward mitigating the excess morbidity and mortality of an incarceration event.Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.

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