• Sean M Stokes, Rebecca Y Kim, Alex Jacobs, Jordan Esplin, Alvin C Kwok, Thomas K Varghese, Robert E Glasgow, Benjamin S Brooke, Finlayson Samuel R G SRG Division of General Surgery, Department of Surgery, University of Utah School of Medicine, Salt Lake City, Utah., and Lyen C Huang.
• Division of General Surgery, Department of Surgery, University of Utah School of Medicine, Salt Lake City, Utah. Electronic address: Sean.stokes@hsc.utah.edu.
• J. Surg. Res. 2020 Jan 1; 245: 396-402.

BackgroundPostoperative overprescribing is common, and many patients will have excess medications. An effective method to encourage disposal is lacking. We hypothesized that a convenient home disposal kit will result in more appropriate disposal of excess opioids.Materials And MethodsWe conducted a single-center prospective observational pilot study to evaluate the effectiveness of a postoperative opioid disposal kit. Patients in the intervention group received an opioid disposal kit and educational handout before discharge from the hospital. At the first follow-up visit, patients completed a survey in which they reported the remaining amount of pain medications from their original prescription and their plan for the excess medication. Patients were asked about risk factors for chronic opioid use. We used multivariable Poisson regression to identify independent factors associated with an increased likelihood of appropriate opioid disposal.ResultsThe survey was offered to 904 patients with a response rate of 91.7%. After excluding those with missing data, 571 patients were included in the study. Overall, 83 (14.5%) patients never filled an opioid prescription, and 286 (60.0%) patients had tablets remaining at the time of the follow-up visit. Among those with tablets remaining, 52 received a home disposal kit, whereas 234 patients with tablets remaining did not. Patients who received the kit were more likely to dispose of opioid medications (54.9% versus 34.8%, relative risk = 1.8, 95% CI 1.3-2.5). No confounders were identified during multivariable analysis that increased a patient's likelihood of disposing excess medications.ConclusionsThe provision of a convenient home disposal kit postoperatively increased patient-reported opioid disposal.Copyright © 2019 Elsevier Inc. All rights reserved.

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