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- Yusuke Yamaba, Osamu Takakuwa, Ziren Wang, Manami Saito, Daisuke Kawae, Misuzu Yoshihara, Eiji Kunii, Yutaka Ito, and Kenji Akita.
- Department of Respiratory Medicine, Nagoya City West Medical Center, Japan.
- Intern. Med. 2020 Dec 15; 59 (24): 3195-3200.
AbstractA 68-year-old man visited our hospital due to anorexia, weight loss and a fever. We diagnosed the patient with disseminated Mycobacterium avium complex (MAC) and confirmed the presence of interferon (IFN)-γ neutralizing autoantibodies (IFN-γAb). His lesions improved following antibiotic therapy, but chylous ascites (CA) developed seven months after treatment. CA was able to be controlled by subcutaneous octreotide and diet therapy. IFN-γAb is recognized as having a critical role in the pathogenesis of disseminated MAC disease, but its clinical features are not fully understood. CA may be a complication that develops during the treatment of disseminated MAC infection.
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