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- Sho Hayashida, Shunsuke Sato, Yuji Shimada, Hironori Tsuzura, Yuji Ikeda, Sho Takahashi, Sho Sato, Nozomi Amano, Ayato Murata, Akihito Nagahara, and Takuya Genda.
- Department of Gastroenterology and Hepatology, Juntendo University Shizuoka Hospital, Japan.
- Intern. Med. 2020 Jan 1; 59 (16): 1977-1981.
AbstractA 45-year-old man with steroid-dependent ulcerative pancolitis was hospitalized with frequent diarrhea, abdominal pain and distension 3 months after induction of golimumab, a tumor necrosis factor-alpha antagonist. Computed tomography showed wall thickening from the stomach to the colon and massive ascites. Peripheral blood test revealed eosinophilia. A large number of eosinophils were observed in the ascites fluid. Although esophagogastroduodenoscopy showed no abnormal findings and colonoscopy showed ulcerative colitis with a Mayo endoscopic subscore of 1, eosinophil infiltration was histologically observed. Based on these findings, we diagnosed him with eosinophilic gastroenteritis and started prednisolone. Consequently, his eosinophil counts and abdominal symptoms dramatically improved.
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