• Timothy R Deer, Corey W Hunter, Pankaj Mehta, Dawood Sayed, Jay S Grider, Tim J Lamer, Jason E Pope, Steven Falowski, David A Provenzano, Michael F Esposito, Konstantin V Slavin, Ganesan Baranidharan, Marc Russo, Navdeep S Jassal, Alon Y Mogilner, Leo Kapural, Paul Verrills, Kasra Amirdelfan, W Porter McRoberts, Michael E Harned, Kenneth B Chapman, Liong Liem, Jonathan D Carlson, Ajax Yang, Rohit Aiyer, Ajay Antony, Michael A Fishman, Adnan A Al-Kaisy, Nick Christelis, Robert M Levy, and Nagy Mekhail.
• Spine and Nerve Center of the Virginias, Charleston, West Virginia.
• Pain Med. 2020 Aug 1; 21 (8): 1581-1589.

ObjectiveTo conduct a systematic literature review of dorsal root ganglion (DRG) stimulation for pain.DesignGrade the evidence for DRG stimulation.MethodsAn international, interdisciplinary work group conducted a literature search for DRG stimulation. Abstracts were reviewed to select studies for grading. General inclusion criteria were prospective trials (randomized controlled trials and observational studies) that were not part of a larger or previously reported group. Excluded studies were retrospective, too small, or existed only as abstracts. Studies were graded using the modified Interventional Pain Management Techniques-Quality Appraisal of Reliability and Risk of Bias Assessment, the Cochrane Collaborations Risk of Bias assessment, and the US Preventative Services Task Force level-of-evidence criteria.ResultsDRG stimulation has Level II evidence (moderate) based upon one high-quality pivotal randomized controlled trial and two lower-quality studies.ConclusionsModerate-level evidence supports DRG stimulation for treating chronic focal neuropathic pain and complex regional pain syndrome.© 2020 American Academy of Pain Medicine. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

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