• Journal of critical care · Dec 2020

    Observational Study

    COVID-19 in critically ill patients in North Brabant, the Netherlands: Patient characteristics and outcomes.

    • F E Aleva, L van Mourik, M E A C Broeders, A J Paling, and de JagerC P CCPCDepartment of Intensive Care Medicine, Jeroen Bosch Hospital, 's-Hertogenbosch, the Netherlands..
    • Department of Respiratory Medicine, Jeroen Bosch Hospital, 's-Hertogenbosch, the Netherlands; Department of Intensive Care Medicine, Jeroen Bosch Hospital, 's-Hertogenbosch, the Netherlands; Department of Respiratory Medicine, Radboud University Medical Center, Nijmegen, the Netherlands. Electronic address: Floor.Aleva@radboudumc.nl.
    • J Crit Care. 2020 Dec 1; 60: 111115111-115.

    PurposeSince the SARS-CoV-2 pandemic, countries are overwhelmed by critically ill Coronavirus disease 2019 (COVID-19) patients. As ICU capacity becomes limited we characterized critically ill COVID-19 patients in the Netherlands.MethodsIn this case series, COVID-19 patients admitted to the ICU of the Jeroen Bosch Hospital were included from March 9 to April 7, 2020. COVID-19 was confirmed by a positive result by a RT-PCR of a specimen collected by nasopharyngeal swab. Clinical data were extracted from medical records.ResultsThe mean age of the 50 consecutively included critically ill COVID-19 patients was 65 ± 10 years, the mean BMI was 29 ± 4.7 and 66% were men. Seventy-eight percent of patients had ≥1 comorbidity, 34% had hypertension. Ninety-six percent of patients required mechanical ventilation and 80% were ventilated in prone position. Venous thromboembolism was recognized in 36% of patients. Seventy-four percent of patients survived and were successfully discharged from the ICU, the remaining 26% died (median follow up 86 days). The length of invasive ventilation in survivors was 15 days (IQR 12-31).ConclusionsThe survival rate of COVID-19 critically ill patients in our population is considerably better than previously reported. Thrombotic complications are commonly found and merit clinical attention.Trial Registration NumberNL2020.07.04.01.Copyright © 2020 The Authors. Published by Elsevier Inc. All rights reserved.

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