• Medicina · Aug 2020

    Can Bioactive Lipid Arachidonic Acid Prevent and Ameliorate COVID-19?

    • Undurti N Das.
    • UND Life Sciences, 2221 NW 5th St, Battle Ground, WA 98604, USA.
    • Medicina (Kaunas). 2020 Aug 19; 56 (9).

    AbstractIt is proposed that the bioactive lipid, arachidonic acid (AA, 20:4 n-6), can inactivate severe acute respiratory syndrome(SARS-CoV-2), facilitate M1 and M2 macrophage generation, suppress inflammation, prevent vascular endothelial cell damage, and regulate inflammation resolution processes based on the timely formation of prostaglandin E2 (PGE2) and lipoxin A4 (LXA4) based on the context. Thus, AA may be useful both to prevent and manage coronavrus disease-2019(COVID-19).

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