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J. Thromb. Haemost. · May 2017
Thrombotic and bleeding outcomes following perioperative interruption of direct oral anticoagulants in patients with venous thromboembolic disease.
- J Shaw, C de Wit, G Le Gal, and M Carrier.
- Department of Medicine, Division of Hematology, The Ottawa Hospital, Ottawa, ON, Canada.
- J. Thromb. Haemost. 2017 May 1; 15 (5): 925-930.
AbstractEssentials Studies evaluating the procedural interruption of direct oral anticoagulants (DOACs) are lacking. We conducted a study of the interruption of DOACs for prior venous thromboembolic disease (VTE). The post-operative risks of recurrent VTE and major bleeding are low in this patient population. A scheme based on half-life and procedure-related bleeding appears safe and efficacious.© 2017 International Society on Thrombosis and Haemostasis.
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