• Internal medicine · Jan 2021

    Case Reports

    A Case of Mycophenolate Mofetil-induced Diffuse Large B-cell Lymphoma in Which a Solitary Lung Nodule Remitted Spontaneously.

    • Hiroshi Kobe, Akihiro Ito, Hiroki Hayata, Keisuke Nishimura, Yasunori Ueda, and Tadashi Ishida.
    • Department of Respiratory Medicine, Ohara Healthcare Foundation, Kurashiki Central Hospital, Japan.
    • Intern. Med. 2021 Jan 1; 60 (1): 131-136.

    AbstractA 76-year-old woman with dermatomyositis was being treated with prednisolone, tacrolimus, and mycophenolate mofetil. There was a solitary lung nodule in the right middle lobe on chest computed tomography at a routine follow-up examination. A transbronchial lung biopsy was performed, and the histopathologic findings indicated diffuse large B-cell lymphoma. An immunodeficiency-associated lymphoproliferative disorder was suspected, and mycophenolate mofetil was stopped without adding any other therapy. Nine months later, the pulmonary nodule had disappeared on chest computed tomography.

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