• Louis Chauvelot, Laurent Bitker, François Dhelft, Mehdi Mezidi, Maciej Orkisz, Eduardo Davila Serrano, Ludmilla Penarrubia, Hodane Yonis, Paul Chabert, Laure Folliet, Guillaume David, Judith Provoost, Pierre Lecam, Loic Boussel, and Jean-Christophe Richard.
• Service de Médecine Intensive Réanimation, Hôpital De La Croix Rousse, Hospices Civils de Lyon, 93 grande rue de la Croix-Rousse, 69004 Lyon, France.
• J Crit Care. 2020 Dec 1; 60: 169-176.

PurposeThe aim of this study was to assess whether the computed tomography (CT) features of COVID-19 (COVID+) ARDS differ from those of non-COVID-19 (COVID-) ARDS patients.Materials And MethodsThe study is a single-center prospective observational study performed on adults with ARDS onset ≤72 h and a PaO2/FiO2 ≤ 200 mmHg. CT scans were acquired at PEEP set using a PEEP-FiO2 table with VT adjusted to 6 ml/kg predicted body weight.Results22 patients were included, of whom 13 presented with COVID-19 ARDS. Lung weight was significantly higher in COVID- patients, but all COVID+ patients presented supranormal lung weight values. Noninflated lung tissue was significantly higher in COVID- patients (36 ± 14% vs. 26 ± 15% of total lung weight at end-expiration, p < 0.01). Tidal recruitment was significantly higher in COVID- patients (20 ± 12 vs. 9 ± 11% of VT, p < 0.05). Lung density histograms of 5 COVID+ patients with high elastance (type H) were similar to those of COVID- patients, while those of the 8 COVID+ patients with normal elastance (type L) displayed higher aerated lung fraction.Copyright © 2020 Elsevier Inc. All rights reserved.

25 keywords...

hide…