• Tracey N Liebman, Natalia Jaimes-Lopez, Yevgeniy Balagula, Harold S Rabinovitz, Steven Q Wang, Stephen W Dusza, and Ashfaq A Marghoob.
• Memorial Sloan-Kettering Cancer Center, New York, New York 10022, USA.
• Dermatol Surg. 2012 Mar 1; 38 (3): 392-9.

BackgroundBasal cell carcinomas (BCCs) can be diagnosed using different dermoscopic modalities.ObjectiveTo evaluate dermoscopic features of BCCs using nonpolarized and polarized dermoscopy to highlight similarities and differences between dermoscopic modalities.Materials And MethodsRetrospective study of 149 BCCs under nonpolarized dermoscopy (NPD), polarized contact dermoscopy (PCD), and polarized noncontact dermoscopy (PNCD). Images were evaluated for a range of dermoscopic colors, structures, and vessels. Features were compared according to histopathologic subtype.ResultsThe most common dermoscopic structures in BCCs across all modalities included globules (50.3-51.0%), dots (49.7-50.3%), white structureless areas (63.1-74.5%), structureless gray-brown areas (24.2-24.8%), and ulcerations (28.2%). The most frequently observed vasculature included arborizing vessels (18.8-38.3%), short fine telangiectasias (SFTs) (73.8-82.6%), and vascular blush (41.6-83.2%). Structures with higher levels of agreement across modalities included pigmented structures and ulcerations. Lower levels of agreement existed between contact and noncontact modalities for certain vascular features. White shiny structures, which include shiny white lines (chrysalis and crystalline structures) (0-69.1%), shiny white areas (0-25.5%), and rosettes (0-11.4%), exhibited no agreement between NPD and polarized modalities.ConclusionsThis study highlights differences in dermoscopic features of BCCs under three dermoscopic modalities. Shiny white lines (chrysalis and crystalline structures) and shiny white areas may be used as additional criteria to diagnose BCCs.© 2011 by the American Society for Dermatologic Surgery, Inc. Published by Wiley Periodicals, Inc.

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