• Carrie A Griffith and Daniel E Hoffmann.
• Akron Veterinary Referral and Emergency Center, 1321 Centerview Circle, Akron, OH 44321.
• J Vet Emerg Crit Care (San Antonio). 2013 Nov 1; 23 (6): 631-6.

ObjectiveTo describe a case of status epilepticus believed to be a consequence of inadvertent intrathecal administration of cefazolin in a dog undergoing a myelogram.Case SummaryA 4-year-old, 6.5 kg, male neutered Dachshund was referred for evaluation of an acute onset hind limb paraparesis. While performing a lumbar myelogram, cefazolin was inadvertently injected into the ventral subarachnoid space. Subsequent refractory seizure activity was attributed to the epileptogenic effects of intrathecally administered cefazolin. Supportive therapy led to eventual complete recovery.New Or Unique Information ProvidedAlthough epileptogenic effects of intrathecally administered cefazolin are well documented in the human and experimental animal model literature, to the authors' knowledge this has not been characterized in the veterinary literature. This case highlights the need to be diligent and mindful when one administers medications, and describes the management of a dog adversely affected as a consequence of a medical error.© Veterinary Emergency and Critical Care Society 2013.

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