• Int. J. Antimicrob. Agents · May 2020

    The epidemiology, diagnosis and treatment of COVID-19.

    • Pan Zhai, Yanbing Ding, Xia Wu, Junke Long, Yanjun Zhong, and Yiming Li.
    • Department of Neurology, Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan, 430073, Hubei, China.
    • Int. J. Antimicrob. Agents. 2020 May 1; 55 (5): 105955.

    AbstractIn December 2019, the outbreak of the novel coronavirus disease (COVID-19) in China spread worldwide, becoming an emergency of major international concern. SARS-CoV-2 infection causes clusters of severe respiratory illness similar to severe acute respiratory syndrome coronavirus. Human-to-human transmission via droplets, contaminated hands or surfaces has been described, with incubation times of 2-14 days. Early diagnosis, quarantine, and supportive treatments are essential to cure patients. This paper reviews the literature on all available information about the epidemiology, diagnosis, isolation and treatments of COVID-19. Treatments, including antiviral agents, chloroquine and hydroxychloroquine, corticosteroids, antibodies, convalescent plasma transfusion and vaccines, are discussed in this article. In addition, registered trials investigating treatment options for COVID-19 infection are listed.Copyright © 2020 Elsevier Ltd. All rights reserved.

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