• Journal of virology · May 2016

    Review

    Zika Virus: New Clinical Syndromes and Its Emergence in the Western Hemisphere.

    • Helen M Lazear and Michael S Diamond.
    • Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA helen.lazear@med.unc.edu diamond@borcim.wustl.edu.
    • J. Virol. 2016 May 15; 90 (10): 4864-4875.

    AbstractZika virus (ZIKV) had remained a relatively obscure flavivirus until a recent series of outbreaks accompanied by unexpectedly severe clinical complications brought this virus into the spotlight as causing an infection of global public health concern. In this review, we discuss the history and epidemiology of ZIKV infection, recent outbreaks in Oceania and the emergence of ZIKV in the Western Hemisphere, newly ascribed complications of ZIKV infection, including Guillain-Barré syndrome and microcephaly, potential interactions between ZIKV and dengue virus, and the prospects for the development of antiviral agents and vaccines.Copyright © 2016, American Society for Microbiology. All Rights Reserved.

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