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- Lisa McKerracher and Matthew J Winton.
- Département de Pathologie et biologie cellulaire, Université de Montréal, 2900 Edouard-Montpetit, Montreal, Quebec, H3T 1J4, Canada. mckerral@patho.umontreal.ca
- Neuron. 2002 Oct 24; 36 (3): 345-8.
AbstractGrowth inhibition in the central nervous system (CNS) is a major barrier to axon regeneration. Recent findings indicate that three distinct myelin proteins, myelin-associated glycoprotein (MAG), Nogo, and oligodendrocyte-myelin glycoprotein (OMgp), inhibit axon growth by binding a common receptor, the Nogo66 receptor (NgR), and likely converge on a common signaling cascade.
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