• Philippe Vichard, Daniel Talon, and Laurent Jeunet.
• Service de Chirurgie Orthopédique Traumatologique et Plastique, CHU-Hôpital Jean Minjoz-25030 Besançon.
• B Acad Nat Med Paris. 2003 Jan 1; 187 (5): 905-18; discussion 918-20.

UnlabelledTo examine whether Sepsis Containment Units are presently in use by French Orthopedic surgeons in a number of hospitals and the subsequent efficacy of these measures in the prevention of risks linked to methicillin resistant Staphylococcus aureus (MRSA), MRSA was used as an example because it is the bacteria most frequently associated with infection in orthopedics. The transient carriage of MRSA on the hands of hospital personnel is the most common mechanism of patient to patient transmission. Consequently, the incidence of nosocomial MRSA in patients can be used to assess the quality of infection control.SettingThe orthopaedic surgery department (104 beds) of a 1. 228 bed, university affiliated public hospital located in eastern France (Besançon).MethodsFirst: a questionnaire was sent out to 71 French university orthopedic departments to investigate the practice in place. Second: to establish whether a significant correlation exists between the colonisation pressure exerted by real imported MRSA, and the number of cases of real acquired MRSA since we know that colonisation pressure of bacteria is a major factor in the prognosis of clinical infection. Third: our orthopedic surgery department was redesigned to study the risks of colonisation pressure with or without Sepsis Containment Units.ResultsFirst: among the 71 orthopedic departments studied, only 11 used a Sepsis Containment Unit. Second: there is a definite, linear relationship between the colonisation pressure exerted in a unit by real imported MRSA and the number of cases of real acquired clinical infection. Third: in the absence of Sepsis Containment Units, the risk of MRSA infections is increased by 160%. Debat: the classical clinical arguments concerning the dangers of hand or aerobic MRSA transmission are confirmed by our figures. The strict use of Sepsis Containment Units prevents contamination of septics by septics. Inversely, the rigorous concentration of means in the Sepsis Containment Units also prevents cross contamination of septics. At question are the psychological and financial inconveniences of Sepsis Containment Units. The results of this experiment, performed in orthopedic surgery, show that the use of Sepsis Containment Units is just as critical in other surgical units: vascular, thoracic, etc., nor should they be overlooked in outpatient and emergency care--often the first step in orthopedic surgery.ConclusionSepsis Containment Units are essential and merit further development.

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