• Josep Montserrat-Capdevila, Pere Godoy, Josep Ramon Marsal, Marta Ortega, Ferran Barbé, Maria Teresa Castañ, María Asunción Seminario, Jesús Pujol, and Miquel Alsedà.
• Consultorio Local de Bellvís, ABS Pla d'Urgell, Atención Primaria, Institut Català de la Salut, Bellvís, Lleida, España; Institut de Recerca Biomèdica (IRB) de Lleida, Lleida, España; Agència de Salut Pública de Catalunya, Departament de Salut, Lleida, España; Facultat de Medicina, Universitat de Lleida, Lleida, España. Electronic address: jmontser@alumni.unav.es.
• Aten Primaria. 2019 Dec 1; 51 (10): 602-609.

ObjectiveThe objective of the study was to know the profile of patients diagnosed with chronic obstructive pulmonary disease (COPD) and who have never been smokers.DesignA transversal study.LocationPrimary Care Centre of Pla d'Urgell (Primary care setting in Lleida, Spain).Participants512 patients older than 40 years with COPD from Primary Care Centre of Pla d'Urgell with a compatible spirometry [forced expiratory volume in one second (FEV1)/forced vital capacity (FVC) ratio <0.7) to the beginning of the study.Main MeasurementsThe dependent variable was de COPD in non-smokers and the independents were variables collected from the information on the respiratory clinical history, the risk factors of the patients and on quality of life. We designed a predictor model of COPD in non-smokers compared to smokers.Results33.2% of COPD patients had never been smokers, 59.4% of whom were women. The average FEV1 for non-smokers was 70.5 (SD=17.1), higher than 62.6 (SD=18.5) for smokers/former smokers (p<0.001). The coverage of pneumococcal vaccination 23V was better in non-smokers (75.3%), p<0.001. COPD in non-smokers (compared to smokers/former smokers) were: mostly women (OR=16.46), older (OR=1.1), with better FEV1 (OR=1.1), better perception of quality, EuroQoL-5D (OR=0.8), with lower prevalence of diabetes (OR=0.5), lower level of studies (OR=0.2), and with fewer previous hospitalizations (OR=0.3).ConclusionsThe study evidences a high proportion of non-smokers in COPD patients. Our study aims that older women with less severity would be associated with an increased risk of COPD in non-smokers. It seems to indicate that COPD in non-smokers would appear at later ages and would be milder than smoking-related COPD.Copyright © 2018 The Authors. Publicado por Elsevier España, S.L.U. All rights reserved.

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