• Aust Prescr · Feb 2019

    Review

    Nitrofurantoin and fosfomycin for resistant urinary tract infections: old drugs for emerging problems.

    • Bradley J Gardiner, Andrew J Stewardson, Iain J Abbott, and Anton Y Peleg.
    • Department of Infectious Disease, Alfred Health and Central Clinical School, Monash University, Melbourne.
    • Aust Prescr. 2019 Feb 1; 42 (1): 14-19.

    Uncomplicated Urinary Tract Infection Is One Of The Most Common Indications For Antibiotic Use In The Community However The Gram Negative Organisms That Can Cause The Infection Are Becoming More Resistant To AntibioticsMany Multidrug Resistant Organisms Retain Susceptibility To Two Old Antibiotics Nitrofurantoin And Fosfomycin Advantages Over Newer Drugs Include Their High Urinary Concentrations And Minimal ToxicityFosfomycin Is A Potential Treatment Option For Patients With Uncomplicated Urinary Tract Infection Due To Resistant Organisms Nitrofurantoin May Be More Effective And Can Be Used For Urinary Infections In Pregnant Women

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