• Luciano Timbó Barbosa, Célio Fernando de Sousa Rodrigues, Raul Ribeiro de Andrade, and Fabiano Timbó Barbosa.
• . Universidade Federal de Alagoas (Ufal), Maceió, AL, Brasil.
• Rev Assoc Med Bras (1992). 2020 Aug 1; 66 (8): 1146-1151.

IntroductionLumbar pain is one of the main reasons for medical consultation, causing the disruption of daily routines due to its disabling nature, thus resulting in social and personal damage. Among the complementary treatments, ozonotherapy offers analgesia to most patients, with reports of complications. However, great questions about its clinical effectiveness have not been answered yet, and there have been reports of serious complications.ObjectiveTo describe the use of ozonotherapy in the treatment of lumbar pain, focusing on its favorable and unfavorable effects, and its analog profile.MethodsA cross-sectional bibliographic research was performed with scientific articles obtained from the Pubmed, LILACS and Scopus database, using the following descriptors: "Ozone", "Therapy", "Lumbar pain", "complication", "Disk herniation", "Guideline", "Protocol", "Standards", "Criteria".ResultsThe researched literature corroborates that, in clinical practice, there is safety in the use of oxygen-ozone therapy through percutaneous injections for the treatment of lumbar pain, especially when compared to surgeries and use of medicines, provided that strict criteria are followed.ConclusionThe procedure is effective and has a favorable analgesic profile. However, it is necessary to produce a medical guideline that will help in its strict and systematic control.

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