• Medicina clinica · Sep 2019

    Multicenter Study Comparative Study

    Comparison between PROFUND and PALIAR indexes in polypathological patients with advanced non-oncologic chronic diseases.

    • Jesús Díez-Manglano, Noelia Gómez-Aguirre, José Velilla-Marco, María Pilar Lambán Aranda, Begoña de Escalante Yangüela, Daniel Fuertes Ruiz, Alfonso García Aranda, Carolina Clemente Sarasa, en nombre de los investigadores del estudio PALIARAGON, and Lista de investigadores del estudio PALIARAGON.
    • Servicio de Medicina Interna, Hospital Royo Villanova, Zaragoza, España; Grupo de Investigación en Comorbilidad y Puripatología de Aragón, Instituto Aragonés de Ciencias de la Salud, Zaragoza, España. Electronic address: jdiez@aragon.es.
    • Med Clin (Barc). 2019 Sep 13; 153 (5): 196-201.

    Background And ObjectiveTo compare the discrimination power of PROFUND and PALIAR indexes for predicting mortality in polypathological patients with advanced non-oncologic chronic disease.Material And MethodsProspective multicentre cohort study. We included polypathological patients with advanced non-oncologic chronic disease, who were admitted to internal medicine departments between July 1st and December 31th, 2014. Data was collected from each patient on age, sex, categories of polypathology, advanced disease, comorbidity, functional and cognitive assessment, terminal illness symptoms, need for caregiver, hospitalisation in the past three and 12 months and number of drugs. We calculated the PROFUND and PALIAR indexes and conducted a 12-month follow-up. We assessed mortality with the Kaplan-Meier survival curves and the discrimination of indexes with the ROC curves.ResultsWe included 213 patients with a mean (standard deviation) age of 83.0 (7.0) years, 106 (49.8%) of whom were female. Mortality at six months was 40.4% and at 12 months 50.2%. Deceased patients scored higher scores on the PROFUND [11.2(4.2) vs 8.5(3.9); P<.001] and PALIAR [6.7 (4.6) vs 3.6(3.1); p<0,001] indexes. The discrimination of PALIAR index at six months (under the curve area 0.734 95%CI 0.665-0.803) was higher than of PROFUND, and there was no difference at 12 months.ConclusionsIn polypathological patients with advanced non-oncologic chronic disease, the PALIAR index had better discrimination power than PROFUND index at 66 months and there were no differences at 12 months.Copyright © 2019 Elsevier España, S.L.U. All rights reserved.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…