• Leticia Gomez-Sanchez, Manuel A Gomez-Marcos, Maria C Patino-Alonso, Jose I Recio-Rodriguez, Marta Gomez-Sanchez, Jesús González-Sánchez, Rosario Alonso-Domínguez, Natalia Sánchez-Aguadero, Jose A Maderuelo-Fernandez, Rafel Ramos, Luis Garcia-Ortiz, Emiliano Rodriguez-Sanchez, and MARK Group.
• Institute of Biomedical Research of Salamanca (IBSAL), Primary Health Care Research Unit, La Alamedilla Health Center, Salamanca, Spain; Health Service of Castilla y León (SACyL), Salamanca, Spain.
• Med Clin (Barc). 2019 Nov 15; 153 (9): 351-356.

Background And ObjectiveThe estimation of cardiovascular risk (CVR) with scores at 30 years old has a special interest in reclassifying in a suitable way <60 year subjects with intermediate CVR. This study analyzes what percentage of patients with intermediate CVR included in the MARK study is reclassified by applying the 30-year Framingham score (FS30). It also analyzes the degree of agreement between the two equations to classify high risk subjects.Patients And MethodsCross-sectional study of 966 subjects included in the MARK study. The CVR was calculated with the two versions of the FS30 (based on lipids and body mass index) for "hard" cardiovascular events in subjects with intermediate CVR.ResultsThe 59% and 61% of the subjects with intermediate CVR would be classified as if they had high CVR to undergo a hard event if we used the FS30 in both versions. 70% of men and 35% of women would be classified as high CVR (p<0.01). The agreement percentage, measured with the Kappa index, between the equations FS30L and FS30BMI to classify the high-risk subjects was 67.9% (in men 67.4% and in women 68.7%).ConclusionsIn subjects with intermediate CVR the FS30 reclassifies more than the half as high RCV, 2 out of 3 men and 1 out of 3 women.Copyright © 2019 Elsevier España, S.L.U. All rights reserved.

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