• Contraception · Feb 2015

    Randomized Controlled Trial Comparative Study

    Nitrous oxide for pain management of first trimester surgical abortion -- a randomized controlled pilot study.

    • Rameet H Singh, Eve Espey, Shannon Carr, Brenda Pereda, Tony Ogburn, and Lawrence Leeman.
    • University of New Mexico School of Medicine Department of Obstetrics and Gynecology, Albuquerque, New Mexico. Electronic address: RHSingh@salud.unm.edu.
    • Contraception. 2015 Feb 1; 91 (2): 164-6.

    ObjectiveThe objective was to determine feasibility of a study comparing mean pain scores between women randomized to nitrous oxide/oxygen (NO) versus oxygen+oral analgesics for trimester surgical abortion.Study DesignPilot randomized controlled trial comparing NO (n=10) versus oxygen+oral analgesics (n=10). Feasibility of subject recruitment, and pain and satisfaction scores on a visual analog scale were evaluated.ResultsFifty-seven percent of eligible women participated. Mean pain scores were similar between groups, and mean satisfaction scores were higher for the NO group (77.5 vs. 46.7, P=.048).ConclusionsThe majority of eligible women agreed to participate in this study evaluating an uncommon pain control intervention.Copyright © 2015 Elsevier Inc. All rights reserved.

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