• Internal medicine · Jan 2013

    Case Reports

    Effects of continuous positive airway pressure therapy in three Japanese patients with obstructive sleep apnea and resistant hypertension.

    • Hiromitsu Sekizuka, Naohiko Osada, and Fumihiko Miyake.
    • Division of Cardiology, Department of Internal Medicine, St. Marianna University School of Medicine, Japan.
    • Intern. Med. 2013 Jan 1; 52 (19): 224122442241-4.

    AbstractThe following three case reports present the effects of 6-month continuous positive airway pressure (CPAP) therapy on blood pressure (BP) in severe obstructive sleep apnea patients with resistant hypertension. Case 1 A 58-year-old woman exhibited a decreased 24-hour BP and changes in the nocturnal BP dipping pattern from non-dipper to dipper. Case 2 A 64-year-old man showed no improvements in nocturnal BP. Case 3 A 78-year-old man with ischemic cardiomyopathy exhibited changes in the nocturnal BP dipping pattern from non-dipper to dipper. These results suggest that 6-month CPAP therapy improves the nocturnal BP dipping status in some patients with obstructive sleep apnea and resistant hypertension.

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