• Annals of family medicine · Sep 2020

    Comparative Study

    Thyroid Stimulating Hormone Stability in Patients Prescribed Synthetic or Desiccated Thyroid Products: A Retrospective Study.

    • Rolake Kuye, Catherine Riggs, Jordan King, Rachel Heilmann, Deanna Kurz, and Jessica Milchak.
    • Kaiser Permanente, Denver, Colorado.
    • Ann Fam Med. 2020 Sep 1; 18 (5): 452-454.

    AbstractThe purpose of this retrospective matched-cohort study was to evaluate the stability of thyroid stimulating hormone (TSH) in patients using synthetic compared with desiccated thyroid products. Patients using a thyroid product for the treatment of hypothyroidism were matched 1:1 on age, sex, race/ethnicity, and had a follow-up period of 3 years after the index date. The primary outcome was percent of in-range TSH values. Over 3 years, TSH values in both groups were in-range 79% of the time (P = 0.905). Our results showed no difference in longitudinal TSH stability between desiccated thyroid products and synthetic levothyroxine.© 2020 Annals of Family Medicine, Inc.

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