• Internal medicine · Jan 2021

    Case Reports

    A Case of Pulmonary Embolism and Splenic Infarction after Minocycline Infusion in a Patient with Polycythemia Vera.

    • Makoto Takeuchi, Takenori Okada, Kouji Iwato, Kazuma Kawamoto, Yuki Ikegami, Yumiko Nakamoto, Naomi Idei, and Norihiko Ohashi.
    • Department of Cardiology, Hiroshima Red Cross Hospital and Atomic-bomb Survivors Hospital, Japan.
    • Intern. Med. 2021 Jan 15; 60 (2): 275-279.

    AbstractA 55-year-old man treated with polycythemia vera visited our hospital, complaining of left abdominal pain and dyspnea. He had received minocycline infusions three weeks earlier for mycoplasma pneumonia. Contrast-enhanced computed tomography revealed pulmonary embolism and splenic infarction. Ultrasonography of the vein in the forearm revealed a thrombus filling the distal brachial veins to the radial veins on both sides. His condition improved after anticoagulant therapy, and right and left shunts were detected on transesophageal echocardiography. This suggested that thrombus in the forearm may have been the source of the embolism.

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