• Hervé Hubert, Déborah Jaeger, Valentine Baert, Christian Vilhelm, Michael Genin, Stéphane Manzo-Silberman, Sonia Sadoune, Franck-Olivier Denayer, François Javaudin, Pierre-Yves Gueugniaud, Karim Tazarourte, Claire Mounier-Vehier, Carlos El Khoury, Tahar Chouihed, and GR-RéAC.
• University of Lille, CHU Lille, ULR 2694 - METRICS (Evaluation des technologies de santé et des pratiques médicales), F-59000 Lille.
• Eur J Emerg Med. 2021 Jan 1; 28 (1): 50-57.

ObjectiveThe aim of the study was to compare outcomes after out-of-hospital cardiac arrest (OHCA) between comparable female and male OHCA cohorts in a large nationwide registry.MethodsThis was a national multicentre retrospective, case-control propensity score-matched study based on French National Cardiac Arrest Registry data from 1 July 2011 to 21 September 2017. Female and male survival rates at D30 were compared.ResultsAt baseline 66 395 OHCA victims were included, of which 34.3% were women. At hospital admission, survival was 18.2% for female patients and 20.2% for male patients [odds ratio (OR), 1.138 (1.092-1.185)]; at 30 days, survival was 4.3 and 5.9%, respectively [OR, 1.290 (1.191-1.500)]. After matching (14 051 patients within each group), female patients received less advanced life support by mobile medical team (MMT), they also had a longer no-flow duration and shorter resuscitation effort by MMT than male patients. However, 15.3% of female patients vs. 9.1% of male patients were alive at hospital admission [OR, 0.557 (0.517-0.599)] and 3.2 vs. 2.6% at D30 [OR, 0.801 (0.697-0.921)], with no statistically significant difference in neurological outcome [OR, 0.966 (0.664-1.407)].ConclusionsIn this large nationwide matched OHCA study, female patients had a better chance of survival with no significant difference in neurological outcome. We also noticed that female patients received delayed care with a shorter resuscitation effort compared to men; these complex issues warrant further specific investigation. Encouraging bystanders to act as quickly as possible and medical teams to care for female patients in the same way as male patients should increase survival rates.Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.

12 keywords...

hide…