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Int J Obstet Anesth · Nov 2020
Case ReportsPeripartum management of a parturient with type 1C (clearance) von Willebrand disease.
- C Prior, K Sims, K Seligman, S Jackson, and A Chau.
- Department of Anesthesia, British Columbia Women's Hospital, Vancouver, BC, Canada. Electronic address: charlieprior@doctors.org.uk.
- Int J Obstet Anesth. 2020 Nov 1; 44: 112-115.
AbstractPeripartum replacement of factor VIII and von Willebrand factor is not usually required in type 1 von Willebrand disease, as the levels of endogenous factors tend to increase to within the normal range as a physiological change of pregnancy. However, there is wide heterogeneity of genotypes and phenotypes associated with type 1 von Willebrand disease. Here, we describe the anesthetic management of a parturient with type 1C von Willebrand disease, a subtype characterized by decreased plasma von Willebrand factor survival.Copyright © 2020 Elsevier Ltd. All rights reserved.
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