• Clin Med (Lond) · Sep 2020

    Non-alcoholic fatty liver disease.

    • Wenhao Li and William Alazawi.
    • Barts Liver Centre, London, UK.
    • Clin Med (Lond). 2020 Sep 1; 20 (5): 509512509-512.

    AbstractNon-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease worldwide. NAFLD is defined by excess fat in the liver and has a multidirectional relationship with metabolic syndrome. The prevalence of NAFLD has risen rapidly in recent years in line with the obesity epidemic and associated increases in type 2 diabetes, hypertension and hypercholesterolaemia. Patients with NAFLD are at risk of cardiovascular disease and cancer, and in a proportion of individuals, NAFLD is associated with liver damage. This article summarises the epidemiology of NAFLD, the clinical approach to risk-assessing patients and briefly outlines current and future management options.© Royal College of Physicians 2020. All rights reserved.

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