• Gerard M O'Reilly, Rob D Mitchell, Biswadev Mitra, Hamed Akhlaghi, Viet Tran, Jeremy S Furyk, Paul Buntine, Holly Bannon-Murphy, Timothy Amos, Maushmi Udaya Kumar, Emma Perkins, Alexandra Prentice, Olivia Szwarcberg, Ashley Loughman, Nicole Lowry, Steven Colwell, Michael P Noonan, Ryan Hiller, Andrew Paton, SmitDe VilliersVEmergency and Trauma Centre, Alfred Health, Melbourne, Victoria, Australia.School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.National Trauma Research Institute, Alfred Health, Melbourne, Vic, Peter A Cameron, and COVED Project Team.
• Emergency and Trauma Centre, Alfred Health, Melbourne, Victoria, Australia.
• Emerg Med Australas. 2021 Feb 1; 33 (1): 114-124.

ObjectiveThe aim of the present study was to describe the epidemiology and clinical features of patients presenting to the ED with suspected and confirmed COVID-19.MethodsThe COVID-19 ED (COVED) Project is an ongoing prospective cohort study in Australian EDs. This analysis presents data from eight sites across Victoria and Tasmania for July 2020 (during Australia's 'second wave'). All adult patients who met criteria for 'suspected COVID-19' and underwent testing for SARS-CoV-2 in the ED were eligible for inclusion. Study outcomes included a positive SARS-CoV-2 test result and mechanical ventilation.ResultsIn the period 1 July to 31 July 2020, there were 30 378 presentations to the participating EDs and 2917 (9.6%; 95% confidence interval 9.3-9.9) underwent testing for SARS-CoV-2. Of these, 50 (2%) patients returned a positive result. Among positive cases, two (4%) received mechanical ventilation during their hospital admission compared to 45 (2%) of the SARS-CoV-2 negative patients (odds ratio 1.7, 95% confidence interval 0.4-7.3; P = 0.47). Two (4%) SARS-CoV-2 positive patients died in hospital compared to 46 (2%) of the SARS-CoV-2 negative patients (odds ratio 1.7, 95% confidence interval 0.4-7.1; P = 0.49). Strong clinical predictors of a positive SARS-CoV-2 result included self-reported fever, non-smoking status, bilateral infiltrates on chest X-ray and absence of a leucocytosis on first ED blood tests (P < 0.05).ConclusionIn this prospective multi-site study from July 2020, a substantial proportion of ED patients required SARS-CoV-2 testing, isolation and enhanced infection prevention and control precautions. Presence of SARS-CoV-2 on nasopharyngeal swab was not associated with death or mechanical ventilation.© 2020 Australasian College for Emergency Medicine.

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